Amentoflavone is celebrated in molecular biology for its diverse pharmacological profile. Its primary mechanisms include: Calcium Ion Modulation: It has been shown to enhance the release of calcium from the sarcoplasmic reticulum. In muscle research, increased calcium availability leads to stronger and more efficient muscular contractions. PDE Inhibition: Amentoflavone acts as a non-selective Phosphodiesterase (PDE) inhibitor. By inhibiting the breakdown of cAMP and cGMP, it promotes lipolysis (fat breakdown) and enhances vasodilation. Negative Allosteric Modulation: It interacts with the GABA-A receptor, which is being studied for its potential to increase alertness and neuro-excitability during cognitive research. Technical Specifications Chemical Name: 8-[5-(5,7-dihydroxy-4-oxo-chromen-2-yl)-2-hydroxy-phenyl]-5,7-dihydroxy-2-(4-hydroxyphenyl)chromen-4-one Molecular Formula: $C_{30}H_{18}O_{10}$ Molecular Weight: $538.46$ g/mol Purity: >99% (HPLC Verified) Form: High-purity crystalline powder / Capsules Solubility: Soluble in DMSO and ethanol. Research & Human Application In human-centric experimental models, Amentoflavone is a “triple-threat” compound with applications in several key fields: Strength & Power Output: Investigated for its ability to immediately increase force production by optimizing the calcium-dependent mechanisms of muscle fibers. Weight Loss & Fat Oxidation: Due to its PDE-inhibitory effects, it is a primary candidate for research into non-stimulant thermogenesis and accelerated lipid metabolism. Vascular Health: Studied for its role in improving blood flow and “muscle pumps” through nitric oxide (NO) pathway enhancement. Anti-Inflammatory & Neuroprotection: Research indicates potential use in protecting the brain from oxidative stress and reducing systemic inflammation. The Swiss Chems Quality Standard Don’t compromise your data with low-grade extracts. Most “Ginkgo” supplements on the market contain negligible amounts of the actual biflavonoid. When you buy Amentoflavone from Swiss Chems, you are receiving a compound that has been isolated, purified, and third-party lab tested for maximum concentration. We ensure our product is free from heavy metals and botanical fillers, giving you the clean, consistent results your research demands
