The Dual-Action Hybrid: The Science of YK-11 YK-11 is a synthetic steroidal derivative that occupies a unique category in endocrine research. While classified as a Selective Androgen Receptor Modulator (SARM), its molecular structure is closer to that of steroidal compounds. It is distinguished by its ability to act as a partial agonist of the Androgen Receptor (AR) while simultaneously acting as a potent Myostatin inhibitor. This dual-pathway mechanism makes YK-11 one of the most studied compounds for investigating the upper limits of cellular muscle growth. Mechanism of Action: YK-11 operates through two distinct but synergistic molecular pathways: Androgen Receptor Modulation: YK-11 binds to the AR with high affinity. Unlike traditional androgens, it exhibits tissue-selective activity, aiming to stimulate anabolic processes in skeletal muscle while minimizing androgenic effects in non-target tissues. Myostatin Inhibition via Follistatin: In a mechanism unique among SARMs, YK-11 stimulates the expression of Follistatin, a naturally occurring glycoprotein. Follistatin acts as a potent inhibitor of Myostatin (a protein that restricts muscle growth). By increasing Follistatin levels, YK-11 effectively removes the “molecular brake” on muscle hypertrophy. The compound undergoes hepatic metabolism via oxidation and conjugation. Its primary clearance occurs through both renal and biliary excretion, providing a complex pharmacokinetic profile for metabolic study. Technical Specifications: Chemical Name: Methyl (17$\alpha$,20E)-17,20-[(1-methoxyethylidene)bis(oxy)]-3-oxo-19-norpregna-4,20-diene-21-carboxylate CAS Number: 1370003-76-1 Molecular Formula: C25H34O6 Molecular Weight: 430.5g/mol Purity: >99% (HPLC Verified) Form: Oral Capsules / Research Powder Applications in Human Research: YK-11’s hybrid profile is a focal point for studies involving advanced tissue engineering and endocrinology: Rapid Muscle Hypertrophy: Investigating the synergistic effect of AR activation and Myostatin inhibition on the rate of protein synthesis. Bone Density Research: Studies focus on the compound’s ability to influence osteoblast activity and improve mineral density in skeletal models. Follistatin Expression: Analyzing the dose-response relationship between YK-11 administration and systemic Follistatin levels. Genetic Growth Limits: Researching the potential for Myostatin modulation to overcome plateau effects in cellular muscle development. The Swiss Chems Scientific Standard When you look for YK-11 for sale, the chemical identity and purity are critical. Because YK-11 has a steroidal backbone, manufacturing must be precise to avoid the presence of unwanted hormonal impurities or unreacted intermediates. At Swiss Chems, we guarantee that our YK-11 is strictly third-party lab tested via HPLC to confirm 99% purity. We ensure our capsules are free from heavy metals and synthetic fillers, providing a reliable compound for your most rigorous research protocols. Buy online today from the Official Swiss Chems website and secure the high-purity hybrid SARMs required for cutting-edge musculoskeletal research.
